Wednesday, 8th February The 42nd Lorne Conference on Protein Structure and Function 2017

• Single‐Particle Cryo‐EM of 200 kDa magnesium channel reveals large conformational changes upon gating - Doreen Matthies
• Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry - Shu Sin Chng
• Defining a second binding site for relaxin on the ectodomain of RXFP1 and its role in activation - Paul Gooley
• Engineering nano discs for membrane protein studies - Gerhard Wagner

• Crystal structure of a sialic acid transporter - Weixiao Wahlgren
• Surface hydrophobicity mapping of individual amyloid-like protein aggregates - Marie N Bongiovanni
• Structural insights into the direct activation of the pro-apoptotic protein Bax by an antibody. - Adeline Y Robin
• A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution - Roland Gamsjaeger
• Hendra virus V protein plasticity enables binding to multiple nuclear transport proteins   - Sarah C Atkinson
• The structural basis of bacterial iron piracy from host ferredoxin - Rhys Grinter
• New insights into the structure and mechanism of action for the large family of autotransporter virulence factors - Jason J Paxman

Presenter:  Alistair Hurst, International Sales Director for EMP Biotech.  

Topic: SMART Chromatography: Protein purification directly from cell-containing feedstreams

 Pathtech, in conjunction with our new supplier, EMP Biotech, are proud to launch the new SMART Chromatography technology (Patent Pending) here in Australia.  Pathtech has been proudly serving the Australian research, life science, and medical communities for over 30 years, with expert support staff, and high quality products, facilitating innovative research and medical care in Australia.  EMP was founded in 1993, with a strong focus on biomolecular purification, and offers high quality consumables and columns to the international scientific community.  EMP’s protein purification resins and columns provide a high quality cost effective alternative for your protein resins and columns, providing high yields, and high levels of purity.  The SMART (or radial flow) chromatography (Patent Pending) range provides scientists the prospect of significantly cutting down intermediate steps in their protein purification process, by eliminating many clean up steps almost entirely, whilst maintaining yields.  SMART Chromatography also offers a faster scale up process, whilst allowing researchers to more easily scale up their protein production.

SMART Chromatography is set to revolutionise the way you purify your proteins.  Would you like to remove the intermediate clean up steps required to purify your proteins, and potentially load lysed cells directly onto your column with little to no clean up steps?

 Let us show you how in our short seminar.  

• Establishing the Molecular Mechanisms of Solute‐Carrier (SLC) transporters: from snapshots to movies - David Drew
• Structural insights into the mechanism of host cell recognition by a type II bacterial toxin complex - Michael J Landsberg
• Birth of the Cool: Protein Allostery by Multitemperature Multiconformer X-Ray Crystallography  - James S Fraser

Location: Lorne Hotel
Address: 176 Mountjoy Parade, Great Ocean Road, Lorne 3232